Metabolic regulation of lipids and fatty acids and risk of cardiometabolic disease”

Our everyday food choices have a major impact on health, by either increasing or decreasing the risk of disease. Lipids and fatty acids are well known to play an important part in metabolic regulation, including the risk of cardiometabolic disease.

Diet is also one of the most important modulators of gut microbiota composition, in which the short-chain fatty acids derived from bacterial fermentation in the gut have been suggested to impact the host’s lipid metabolism. However, there is a lack of mechanistic insights into their impact on lipid metabolism and metabolic regulation.

Interindividual differences in the response to environmental stimuli, including the diet, metabolic regulation, and risk profiles is a focus area within the field of molecular nutrition, aiming at a personalized nutrition or precision nutrition approach to prevention and treatment of diet-related diseases.