YOUR DENTIST MAY DIAGNOSE YOUR SYSTEMIC DISEASES BEFORE ANYONE ELSE

World Health Organization defines oral health in terms of general, physical, psychological and social well-being. Teeth and gums speak volumes about the overall physiological well-being. The manifestation of our internal health can be observed through notable changes in teeth, gums or tongue. A similar manifestation has been seen in a case of tooth enamel defect associated with renal disease called Nephrocalinosis.

Enamel formation or Amelogenesis is a systematic process of tooth enamel deposition. Any disturbance in this process can lead to Tooth Discoloration, Hypocalcification, Hypomaturation, Fragility, Delayed/Unerupted Teeth etc. It is controlled by genetic function due to which a genetic mutation is likely to cause the disorder. A British Medical Journal article found that one of the gene mutations associated with Amelogenesis Imperfecta is also associated with genetic disorder of Nephrocalcinosis. It is a disease state known for too much deposition of calcium in kidneys in forms of Calcium Oxalate and Calcium Phosphate. This process can impair the kidney functions and can also cause kidney stones.

The possibility of common genetic mutation makes it essential to understand the disorders and its relationship. Systematic scoring of both tooth and kidney symptoms would help to discriminate both the conditions and will allow for early diagnosis. Hence, it is recommended that:

1. All patients with Amelogenesis Imperfecta should have detailed renal examination

2. All patients with Nephrocalcinosis should be referred for oral examination.