Faculty

Introduction and Education

Dr. Devlina Ghosh, Ph.D., MBA, MSc (Biochemistry) Gold Medallist is an Assistant Professor of Biochemistry at Saraswati Dental College and Hospital, Lucknow, India. She worked as Senior Research Specialist at the Johns Hopkins University, School of Medicine, Baltimore, USA for more than 8 years. She has published many research papers in high impact scientific journals such as Nature Methods, Nature Communication, Proceedings of the National Academy of Sciences (PNAS) among others. Her research interests lie at the intersection of  inflammation, macrophage activation, and metabolic regulation, particularly understanding the intricate mechanisms underlying immune cell activation and their role in the pathophysiology of inflammatory diseases.

Some of her key publications are-

1. Devlina Ghosh*, Alok Kumar.  Harnessing Mitophagy for Therapeutic Advances in Aging and Chronic Neurodegenerative Diseases. Neuroglia 2024, 5(4), 391-409; *Corresponding Author

2. Devlina Ghosh*, Alok Kumar. Chapter 11- Anxiety and Depression-Related Problems Associated with Adolescents. Editors: Aditi Singh and Abhishek Nandy, Lifestyle Diseases in Adolescents: Addressing Physical, Emotional and Behavioral Issues, Bentham Publications 2024, Pages 158-178, ISBN 978-981-5274-40-0 *Corresponding Author

3. Devlina Ghosh*, Gajendra Singh, Prabhaker Mishra, Aditi Singh, Alok Kumar, Neeraj Sinha. Alteration in mitochondrial dynamics promotes the proinflammatory response of microglia and is involved in cerebellar dysfunction of young and aged mice following LPS exposure, Neuroscience Letters, Volume 807, 2023, 137262, (IF 3.2). *Corresponding Author

4. Devlina Ghosh*, Aditi Singh, Alok Kumar, Neeraj Sinha. High mobility group box 1 (HMGB1) inhibition attenuates lipopolysaccharide-induced cognitive dysfunction and sickness-like behavior in mice. Immunologic Research 70, 633–643 (2022) (IF 4.4). *Corresponding Author

5. Jonathan P Ling, Christopher Wilks, Rone Charles, Devlina Ghosh, Lizhi Jiang, Clayton P., Santiago, Bo Pang, Anand Venkataraman, Brian S Clark, Abhinav Nellore, Ben Langmead, Seth Blackshaw.  ASCOT identifies key regulators of neuronal subtype-specific splicing. Nature Communications (Reference Number: NCOMMS-19-15158)  2020 Jan 9;11(1):137 (IF 17.6).

6. GuanDa Syu, ShihChin Wang, Guangzhong Ma, Shuang Liu, Donna Pearce, Atish Prakash,Brandon Henson, LienChun Weng, Devlina Ghosh, Pedro Ramos, Daniel Eichinger, Ignacio Pino, Xinzhong Dong, Jie Xiao, Shaopeng Wang, Nongjian  Tao, Kwang Sik Kim, Prashant J. Desai, Heng Zhu. Development and Application of a High-Content Virion Display Human GPCR Array. Nature Communications (Reference number: NCOMMS-18-27774), 2019, (IF 17.6)

7. Anand Venkataraman, Kun Yang, Jose Irrizary, Mark Mackiewicz, Paolo Mita, Zheng Kuang, Lin Xue, Devlina Ghosh, 43 authors....Ignacio Pino, Heng Zhu,Seth Blackshaw. A toolbox of immunoprecipitation-grade monoclonal antibodies against human transcription factors. Nature Methods, NMETH-RS30540, 2018, (IF 47.9)

8. Amy F. Weil, Devlina Ghosh, Yan Zhou, Lauren Seiple, Moira A. McMahon, Adam M. Spivak, Robert F. Siliciano and James T. Stivers. Uracil DNA glycosylase initiates degradation of HIV-1 cDNA containing misincorporated dUTP and prevents viral integration. Proceedings of the National Academy of Sciences of the United States of America. 5;110(6):E448-57. doi: 10.1073/pnas.1219702110. Epub 2013, (IF 11.1).

9. Devlina Ghosh*, Aditi Singh, Neeraj Sinha, Chapter 2 - Immunological Genes Expression in the Aged Brain, Editor: Sunil Kumar, The Molecular Immunology of Neurological Diseases, Academic Press, 2021, Pages 15-27, ISBN 9780128219744 *Corresponding Author

10. Devlina Ghosh*, Alok Kumar, Neeraj Sinha, Chapter 6 - Targeted genome editing: a new era in molecular biology, Editors: Sukanta Mondal, Ram Lakhan Singh, Advances in Animal Genomics, Academic Press, 2021, Pages 75-89, ISBN 9780128205952 *Corresponding Author

11.Devlina Ghosh, Bingxin Bai, Qun Ji, Soumya Palliyil, Guang Yang, Alok Kumar, Abhishek Saxena, State-of-the-art preclinical evaluation of COVID-19 vaccine candidates. Exploration of Immunology 2021; 1:440-60.

12. Alok Kumar*, Devlina Ghosh*, Ram Lakhan Singh. Amyotrophic Lateral Sclerosis and Metabolomics: Clinical Implication and Therapeutic Approach. Journal of Biomarker, dx.doi.org/10.1155/2013/538765, 2013. * Authors equally contributed