A patient reported to our department with a chief complaint of reduced mouth opening and ulcer in oral cavity since 4-5 months and diagnosed as Pemphigus Vulgaris and was treated for the same.
Pemphigus vulgaris (PV) is an autoimmune, intraepithelial, blistering disease affecting the skin and mucous membranes and is mediated by circulating autoantibodies directed against keratinocyte cell surfaces.
Pemphigus vulgaris is a blistering disease that initially presents on the oral mucosa in 80% of cases. These intraoral blisters often rupture, leaving painful erosions.
Cutaneous lesions may appear in about 75% of patients with PV after the first oral blisters have presented. Management with Systemic Corticosteroid was done